Comparative Study on Wound Healing Using Potash-table Salt Mixture and Honey on Albino Rats.

FN Oguwike, CM Nwozor1, CN Onwurah, MC Olisah, N Orjiewulu

Abstract


Background: Honey is produced by bees and is widely
consumed in Nigeria. It is used in wound management.
Potash salt and table salt refer to potassium chloride (KCL)
and sodium chloride (NaCl) respectively.
Objective: This study was undertaken to compare the rate
of wound healing using a mixture of potash-table salt and
honey on albino rats.
Methods: Twenty four healthy adult albino rats of Wistar
strain weighing between 180-220g were used in the study.
They were randomly assigned into three groups of 8 rats
each. Group A served as control and received normal saline
only. Group B received topical application of honey. Group C
was treated with a mixture of potash-table salt. Two ml of
blood samples were collected by cardiac puncture at the
end of one month and the following haematological tests
were carried out: total white blood cell count (WBC),
platelet count and white blood cell differentials.

Results: Results showed that potash-table salt healed the
wound faster than honey when applied on wound. The WBC
count in test groups (B & C) were elevated with values of
4,995 ± 563 in group B and 5,337 ±44 in group C compared
with3,716 ± 435 for control. Platelet count in test rats were
also elevated with values of 201.3 ± 2.9 (Group B), 193.8 ±
13.0 (Group C) compared with 168 ±76 (control). The white
blood cell differential count showed significant increase in
neutrophil and monocyte, a significant decrease in
lymphocyte and eosinophil compared with the control
group. There was no change in basophil.

CONCLUSION: It is concluded that wound healing is faster in
potash-table salt treated group than in honey treated
group.


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